

Dan Katō, on the other hand, shared her views, and as their relationship developed he confided with her his dreams of becoming Hokage so that he could bring change to Konoha and protect his loved one from death. Hiruzen, the Third Hokage, agreed with her arguments, but could not dedicate resources to the necessary implementation due to the ongoing war. Tsunade began advocating for the inclusion of medical-nin on all four-man squads in order to avoid future deaths like Nawaki's. He died the next day, a casualty of the ongoing Second Shinobi World War, thus returning the necklace to her. On Nawaki's twelfth birthday, Tsunade kissed his forehead and gave him Hashirama's necklace in the hopes that it would help him achieve his dream.

Tsunade's younger brother, Nawaki dreamed of someday becoming Hokage so that he could protect Konoha, their grandfather's legacy. Tsunade gives Hashirama's necklace to Dan. Despite this remark, Jiraiya had a certain interest in Tsunade from their first meeting, which only increased after her breasts developed when she nearly killed him for spying on her while she bathed, he was forced to be more discrete about his interests.

When Jiraiya failed to acquire a bell during the team's first bell test, Tsunade teased him, prompting him to criticise her flat chest. After she graduated from Konoha's Academy, Tsunade was teamed with Orochimaru and Jiraiya under the leadership of Hiruzen Sarutobi. Tsunade inherited his necklace when he died. Hashirama doted on Tsunade when she was very young because she was his first grandchild, and found her deviance and her adoption of his own gambling habits highly amusing. Because Hashirama was the First Hokage of Konohagakure, Tsunade is called "Princess" ( 姫, Hime). Tsunade is the granddaughter of Hashirama Senju and Mito Uzumaki. 10.1.2 Naruto Shippūden the Movie: The Will of Fire.8.4 Konoha Hiden: The Perfect Day for a Wedding.

